To test if a proprietary herbal formula is effective in treating common warts.

Common Warts

  • Common warts are contagious epithelial tumours commonly occurring in areas prone to trauma, such as knees, elbows, hands and feet and caused by more than 100 types of Human Papilloma Virus (HPV).
  • Transmission is by skin-to-skin inoculation however the mechanisms are poorly understood.
  • Time between infection and manifestation of visible warts may vary from days to weeks.
  • Resistance to clearance of warts is due to cell-mediated immune responses.
  • Herbs have been used traditionally to treat warts however few have been subject to rigorous clinical trials.
Wart on Human Skin
Wart on Human Skin

Human Papilloma Virus (HPV)
Human Papilloma Virus (HPV), Giant verrucous exophytic nodule

3d model of Human Papilloma Virus

Clinical Trial Design and Method


  • Males and females between the ages of 18 –70.
  • Diagnosis of benign warts verified by a Medical Practitioner.
  • No serious pre-existing medical condition(s).


  • Wart size and number as measured by a visual comparison of the photographs before and after treatment and classified as:
    – No Change: there was no apparent change in the warts
    – Partially Cleared: up to 50% of the warts reduced or cleared
    – Almost Cleared: more than 50% of the warts reduced or cleared
    – Totally Cleared: all sign of warts had disappeared.
  • A questionnaire on general wellbeing, physical activity and State–Trait Anxiety.


  • Participants were randomised to either the active or no intervention (control) groups.
  • 8 mls of the active intervention was taken orally twice daily with food for 12 weeks.
  • A “no intervention” rather than a placebo group was used as it was not possible to produce a credible placebo with a similar appearance and taste to the active formula.
The study was approved by the Bay of Plenty Ethics Committee.


The wart size/number in the active group were greatly reduced compared to the control group. This was highly statistically significant (p = 0.0007). There was no statistical difference in the responses to the questionnaires between the two groups at baseline or after 12 weeks.


There were no serious adverse reactions. Minimal adverse reactions included increase in flatulence and looser stools initially when taking the herbs. There were some comments about the strong taste.


There is evidence for the effectiveness of this herbal formula
in reducing/clearing common warts.

The results were measured by a visual comparison of the photographs before and after treatment


Principal Researcher: Karina Hilterman
Tel: +61 400 019 567

Research Assistant: Elizabeth Higgs
Monitor: Dr. Nicky Baillie
Statisticians: Elizabeth Robinson & Joanna Stewart


• The Trustees of the Lavender Hill Research Trust
• Kerry Bone, Director of Mediherb Australia, for his helpful advice and for manufacturing and donating the Lavender Hill HPV Herbal Formula used in this clinical trial

Karina wishes you healthy ideas and good humour in
A Handful of Herbs.         Enjoy!




© Karina Hilterman
Melbourne, Australia


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